Lethal concentration of Golden Sea Cucumber killed Vibrio cholerae

Introduction: Diarrhea is still a considerable health problem today, especially in developing countries, including Indonesia. One common etiology of diarrhea Vibrio cholerae, which causes many problems, such as inappropriate use antibiotics antibiotic resistance. The golden sea cucumber (Stichopus hermanii) has antibacterial potential against cholera. This study aims to determine the effect and lethal concentration extract on growth cholerae bacteria.Methods: research an experimental laboratory using post-test-only control group design method. Dilution conducted, where six groups are consisting 4 treatment two groups. 100%, 50%, 25%, 12.5%, while for positive tetracycline distilled water negative control.Results: results this indicate that cucumbers can inhibit bacteria, evidenced by dilution test, higher extract, more bacteria inhibited its growth. With value p = 0.001. obtained from through test starting 25%.Conclusion: Golden regardless concentration.